BDBM50262842 Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetamide::CHEMBL514692

SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1

InChI Key InChIKey=FLHCENWREGCSHY-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50262842   

TargetPhospholipase A2 group V(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IID secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IID secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 890nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIF secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIF secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2 group V(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup 10 secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262842(Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzy...)
Affinity DataIC50: 950nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed