BDBM50262539 (3S,5S)-1-benzyl-5-((R)-2-((1R,3aS,7aR)-4-(2-((3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)propyl)-3-hydroxy-3-methylpyrrolidin-2-one::CHEMBL449990

SMILES C[C@H](C[C@H]1C[C@](C)(O)C(=O)N1Cc1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C

InChI Key InChIKey=NZGHXKMUEBZPLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262539   

TargetVitamin D3 receptor(Human)
Tokyo University of Agriculture and Technology

Curated by ChEMBL
LigandPNGBDBM50262539((3S,5S)-1-benzyl-5-((R)-2-((1R,3aS,7aR)-4-(2-((3S,...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at VDR in human HL60 cells assessed as effect on 1,25-(OH)2-D3-induced cell differentiation by NBT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo University of Agriculture and Technology

Curated by ChEMBL
LigandPNGBDBM50262539((3S,5S)-1-benzyl-5-((R)-2-((1R,3aS,7aR)-4-(2-((3S,...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity assessed by differentiation of 1,25-D3-induced HL60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed