BDBM50262492 CHEMBL4088036

SMILES CCCCc1cc(OC2CCN(CCCCNS(=O)(=O)CC)CC2)c2ncccc2c1

InChI Key InChIKey=YIJMYSUOYUNZGL-UHFFFAOYSA-N

Data  3 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50262492   

TargetMuscarinic acetylcholine receptor M1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]AF-DX 384 from recombinant human M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]-Dofetilide from recombinant human ERG expressed in CHOK1 cell membranes incubated for 4 hrs under dark condition by luminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]mesulergine from recombinant human 5-ht2B expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]mesulergine from recombinant human 5-ht2C expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262492(CHEMBL4088036)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]prazosin from rat salivary gland adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed