BDBM50262023 CHEMBL4071991

SMILES Cc1ccc(cc1)[C@@H]1CN(C[C@H]1c1ccc(cc1)C#N)C(=O)[C@H]1CC[C@H](CN)CC1

InChI Key InChIKey=QHWVHFCEYMEGCM-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262023   

TargetAmine oxidase [flavin-containing] A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in supersomes using kynuramine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in supersomes using kynuramine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataKd:  22nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed