BDBM50261656 CHEMBL3347578

SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(O)=O

InChI Key InChIKey=IAOFKRFVYOFYTI-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261656   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataKd:  3.20nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataKd:  8.5nMAssay Description:Inhibition of p53 binding to MDMX (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50: 20nMAssay Description:Inhibition of human MDM2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed