BDBM50261646 (R)-3-Amino-5-(2-(1-methoxypropan-2-ylamino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)quinoxalin-2(1H)-one::CHEMBL469235

SMILES COC[C@@H](C)Nc1nc(Oc2cccc3[nH]c(=O)c(N)nc23)cc(n1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=JRFCLGQHXPJZTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261646   

LigandPNGBDBM50261646((R)-3-Amino-5-(2-(1-methoxypropan-2-ylamino)-6-(4-...)
Affinity DataIC50: 0.300nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of pH 5 acid-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50261646((R)-3-Amino-5-(2-(1-methoxypropan-2-ylamino)-6-(4-...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed