BDBM50261634 CHEMBL4097045

SMILES Clc1ccc(NC(=O)c2c(N=Cc3ccc4ccccc4c3)c(C#N)c3CCCn23)cc1

InChI Key InChIKey=CHOFHDGORCPUPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261634   

TargetProstaglandin G/H synthase 2(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261634(CHEMBL4097045)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261634(CHEMBL4097045)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed