BDBM50261164 CHEMBL4103221

SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12

InChI Key InChIKey=GGRVRRFOVWKWMD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50261164   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 23nMAssay Description:Inhibition of human CDK1/CyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 319nMAssay Description:Inhibition of human CDK7/CyclinH/MAT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CDK4/CyclinD3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 27nMAssay Description:Inhibition of human CDK9/CyclinT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50261164(CHEMBL4103221)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CDK6/CyclinD3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed