BDBM50260251 CHEMBL489551::olean-12-en-3beta,24-diol

SMILES CC1(C)CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2C1

InChI Key InChIKey=NTWLPZMPTFQYQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260251   

TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50260251(olean-12-en-3beta,24-diol | CHEMBL489551)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50260251(olean-12-en-3beta,24-diol | CHEMBL489551)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50260251(olean-12-en-3beta,24-diol | CHEMBL489551)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed