BDBM50260042 CHEMBL4064534

SMILES CN(C)C\C=C\C(=O)Nc1cc(ccc1C)-n1c2c(ccc3ccc(cc23)-c2cnn(C)c2)ccc1=O

InChI Key InChIKey=JNHXDBIEQOIKLK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50260042   

TargetSerine/threonine-protein kinase pim-2(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length GST-tagged human PIM2 expressed in baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of GST-tagged human DDR1 catalytic domain (440 to 876 residues) expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human DDR2 cytoplasmic domain (427 to 855 residues) expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant full length His-tagged human PIM1 expressed in baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of recombinant full length His-tagged human BMX cytoplasmic domain expressed in baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50260042(CHEMBL4064534)
Affinity DataIC50: 911nMAssay Description:Inhibition of recombinant full length His-tagged human BTK cytoplasmic domain expressed in baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed