BDBM50259375 4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-3-carboxamide::CHEMBL513820

SMILES NS(=O)(=O)c1nnc(NC(=O)c2nn(c(c2C(=O)c2ccccc2)-c2ccccc2)-c2cccc(I)c2)s1

InChI Key InChIKey=AMAKPAWXPWLJCM-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259375   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataIC50: 360nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataIC50: 520nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataKi:  136nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259375(4-Benzoyl-1-(3-iodophenyl)-5-phenyl-N-(5-sulfamoyl...)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed