BDBM50259325 CHEMBL467098::Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazole-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES CCOC(=O)c1c(nn(c1-c1ccccc1)-c1cccc(N)c1)C(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=MOZFIGJRXOUTFH-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50259325   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259325(Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,...)
Affinity DataIC50: 13nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259325(Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,...)
Affinity DataIC50: 210nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259325(Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,...)
Affinity DataIC50: 55nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259325(Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,...)
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259325(Ethyl-1-(3-aminophenyl)-5-phenyl-3-(5-sulfamoyl-1,...)
Affinity DataKi:  4.09E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed