BDBM50259007 (R)-2-(4'-((4-isobutyrylphenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid::CHEMBL511203::N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}sulfonyl)-D-valine

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(COc2ccc(cc2)C(=O)C(C)C)cc1)C(O)=O

InChI Key InChIKey=JGTIIKHYSZFICL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259007   

LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 100nMAssay Description:Inhibition of aggrecanase1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 915nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of aggrecanase2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007(N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed