BDBM50258678 1-(3-(4-chlorophenyl)-5-sulfamoyl-1H-indole-2-carboxamido)-2,4,6-trimethylpyridinium perchlorate::1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol-2-yl]carbonyl}amino)-2,4,6 trimethylpyridinium perchlorate::CHEMBL513854

SMILES Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(cc3c2-c2ccc(Cl)cc2)S(N)(=O)=O)c(C)c1

InChI Key InChIKey=OLTPRSGJHXAYBO-UHFFFAOYSA-O

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258678   

TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258678(1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol...)
Affinity DataKi:  0.960nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258678(1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258678(1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol...)
Affinity DataKi:  20.9nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258678(1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol...)
Affinity DataKi:  29nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258678(1-({[5-(Aminosulfonyl)-3-(4-fluorophenyl)-1H-indol...)
Affinity DataKi:  77nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed