BDBM50258470 CHEMBL4071451

SMILES Fc1ccc2[nH]cc(C3=CCN(CCNS(=O)(=O)c4ccc5ccccc5c4)CC3)c2c1

InChI Key InChIKey=MJKPZFAVGMHXNU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258470   

TargetSodium-dependent serotonin transporter(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50258470(CHEMBL4071451)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK-293 cell membranes after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50258470(CHEMBL4071451)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-methylspiperone from human D2 receptor expressed in CHO-K1 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50258470(CHEMBL4071451)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50258470(CHEMBL4071451)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50258470(CHEMBL4071451)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed