BDBM50257877 CHEMBL4067851

SMILES Nc1nc(N2CCC(CC2)S(N)(=O)=O)c2c(c[nH]c2n1)C#N

InChI Key InChIKey=WWYWTCGTQHTFSL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257877   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257877(CHEMBL4067851)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of IKKalpha in human U2OS cells assessed as decrease in FCS induced p100 phosphorylation at ser866/870 residues preincubated for 1 hr foll...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257877(CHEMBL4067851)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed