BDBM50257825 CHEMBL4100931

SMILES Cc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(N)nc3[nH]cc(C#N)c23)cc1

InChI Key InChIKey=GUBLWPFJYWDJRS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257825   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257825(CHEMBL4100931)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257825(CHEMBL4100931)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of IKKalpha in human U2OS cells assessed as decrease in FCS induced p100 phosphorylation at ser866/870 residues preincubated for 1 hr foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed