BDBM50257124 CHEMBL4070873

SMILES CNCCCn1c2-c3ncc(OC)cc3C(=O)c2c2ccc(F)cc2c1=O

InChI Key InChIKey=BNRFZTXOBLEOGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257124   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50257124(CHEMBL4070873)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of recombinant human TDP2 using 3'-labeled alpha-[32P]-cordycepin as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50257124(CHEMBL4070873)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded DNA containing a 3'-phosphotyrosine as substrate after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2019
Entry Details Article
PubMed