BDBM50256379 CHEMBL482356::methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-azaspiro[5.5]undecane-4-carbodithioate

SMILES CSC(=S)N1CC2(CCCCC2)CO\C1=N/c1ccc(Cl)c2ccccc12

InChI Key InChIKey=CZNZAYFZVJFITK-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50256379   

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-az...)
Affinity DataIC50: 8nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells assessed as inhibition of cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-az...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to mouse CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-az...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-az...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed