BDBM50256043 (Z)-3-bromohymenialdisine::CHEMBL480350::Hymenialdisine, 10

SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c(Br)c(Br)c12

InChI Key InChIKey=ZITKTAJHKVYGTC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50256043   

TargetCyclin-dependent kinase 5 activator 1(Human)
Genomics Institute of The Novartis Research Foundation

LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 56nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Genomics Institute of The Novartis Research Foundation

LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 530nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Genomics Institute of The Novartis Research Foundation

LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 51nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 530nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50256043(CHEMBL480350 | Hymenialdisine, 10 | (Z)-3-bromohym...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Chk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed