BDBM50256004 4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]-8-oxo-4,5,6,7,8,9-hexahydro-3-thia-7,9-diaza-cyclopenta[a]azulene-1-carbonitrile::CHEMBL480187

SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(csc3c12)C#N

InChI Key InChIKey=DFOZXVZCZUBSOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256004   

TargetSerine/threonine-protein kinase Chk1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50256004(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)
Affinity DataIC50: 29nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50256004(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)
Affinity DataIC50: 29nMAssay Description:Inhibition of Chk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed