BDBM50255786 CHEMBL4076777

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2c1ccn(n1)-c1ccc(F)cc1)C(=O)ON1C(=O)CCC1=O

InChI Key InChIKey=FNIBKVOGYHDUDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255786   

TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed