BDBM50255522 Ac-ARTKQTARKSTGGK(CoA)APRKQL::CHEMBL526343

SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#16]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#8])C([#6])([#6])[#6]-[#8]P([#8])(=O)[#8]P([#8])(=O)[#8]-[#6]-[#6@H]-1-[#8]-[#6@H](-[#6@H](-[#8])-[#6@@H]-1-[#8]P([#8])([#8])=O)-n1cnc2c(-[#7])ncnc12)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](-[#6])=O)-[#6@@H](-[#6])-[#8])-[#6@@H](-[#6])-[#8])-[#6@@H](-[#6])-[#8])-[#6](-[#8])=O

InChI Key InChIKey=GUQVWURUSIGOAP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50255522   

TargetHistone acetyltransferase KAT5(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50255522(Ac-ARTKQTARKSTGGK(CoA)APRKQL | CHEMBL526343)
Affinity DataIC50: 7.96E+4nMAssay Description:Inhibition of recombinant Tip60 (1-513) expressed in Escherichia coli BL21 (DE3) by liquid scintillationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50255522(Ac-ARTKQTARKSTGGK(CoA)APRKQL | CHEMBL526343)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of recombinant p300More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50255522(Ac-ARTKQTARKSTGGK(CoA)APRKQL | CHEMBL526343)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of PCAF HAT domain (493-658) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50255522(Ac-ARTKQTARKSTGGK(CoA)APRKQL | CHEMBL526343)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant FLAG-tagged human PCAF expressed in Baculovirus expression system using histone peptide as substrate after 10 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase(Tetrahymena thermophila (strain SB210))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50255522(Ac-ARTKQTARKSTGGK(CoA)APRKQL | CHEMBL526343)
Affinity DataIC50: 500nMAssay Description:Inhibition of Tetrahymena Gcn5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed