BDBM50255152 CHEMBL520099::N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4''-yl)methyl]pyrrolidin-3'-yl)-N2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride

SMILES Cc1cc(C[C@H]2CNC[C@H]2NCCNCCc2cccc(F)c2)cc(N)n1

InChI Key InChIKey=XWUXWXKCZGELTA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255152   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255152(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4''-yl...)
Affinity DataKi:  551nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255152(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4''-yl...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255152(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4''-yl...)
Affinity DataKi:  1.64E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed