BDBM50255151 CHEMBL481420::N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4'-yl)methyl]pyrrolidin-3'-yl)-N2-(4'-chlorobenzyl)ethane-1,2-diamine Tetrahydrochloride

SMILES Cc1cc(C[C@H]2CNC[C@H]2NCCNCc2ccc(Cl)cc2)cc(N)n1

InChI Key InChIKey=JTNZXGSNHWDNPB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255151   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255151(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4'-yl)...)
Affinity DataKi:  1.88E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255151(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4'-yl)...)
Affinity DataKi:  1.41E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255151(N1-(((+/-)-4'-[(2''-Amino-6''-methylpyridin-4'-yl)...)
Affinity DataKi:  2.32E+5nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed