BDBM50254986 5-bromo-1H-indazol-3-amine::CHEMBL465091::EN300-223999

SMILES c1cc2c(cc1Br)c(n[nH]2)N

InChI Key InChIKey=OMPYFDJVSAMSMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254986   

TargetTyrosine-protein kinase JAK2(Human)
Sgx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50: 2.32E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed