BDBM50254745 CHEMBL463864::N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-N5-((R)-1-(4-fluorophenyl)ethyl)chroman-5,7-dicarboxamide

SMILES C[C@@H](NC(=O)c1cc(cc2OCCCc12)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC1)c1ccc(F)cc1

InChI Key InChIKey=BOCRENYPEJKZOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254745   

TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254745(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 740nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254745(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed