BDBM50254580 CHEMBL480009::N-ethyl-5-methyl-N-phenyl-1-(2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide

SMILES CCN(C(=O)c1cc(C)n(n1)-c1ccccc1C(=O)N1CCc2ccccc2C1)c1ccccc1

InChI Key InChIKey=DNHJKFTYIWNMAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50254580   

TargetApoptosis regulator Bcl-2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254580(N-ethyl-5-methyl-N-phenyl-1-(2-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of GST fused Bcl-2 binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed