BDBM50254425 CHEMBL4067996

SMILES Fc1ccc(Nc2n[nH]c3cc(OC(F)(F)F)cnc23)nc1

InChI Key InChIKey=QITDMZAZRQGDJZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254425   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50254425(CHEMBL4067996)Copy SMILESCopy InChI

Affinity DataIC50: 2.54E+3nMAssay Description:Antagonist activity at human TRPA1 by calcium flux based FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
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TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Pfizer

Curated by ChEMBL

LigandBDBM50254425(CHEMBL4067996)Copy SMILESCopy InChI

Affinity DataIC50: 813nMAssay Description:Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL