BDBM50253549 3-(4-Chlorophenyl)-8-(1H-indol-3-ylmethyl)-8-azabicyclo[3.2.1]octan-3-ol::CHEMBL495129::endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo-[3.2.1]octan-3-ol

SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc(Cl)cc1

InChI Key InChIKey=AXPWNFAVTPIWHV-UHFFFAOYSA-N

Data  10 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50253549   

TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataIC50: 48.3nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataIC50: 12.3nMAssay Description:Antagonist activity at dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  15.5nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  33.4nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  3.01E+3nMAssay Description:Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi:  4.77E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253549(endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed