BDBM50253285 4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-1H-pyrrole-2-carboxamide::CHEMBL493091::N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-4-bromo-1H-pyrrole-2-carboxamide

SMILES CN(C)CCCOc1ccc(CCNC(=O)c2cc(Br)c[nH]2)cc1Br

InChI Key InChIKey=MOWCGUQGNSAZSR-UHFFFAOYSA-N

Data  5 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50253285   

TargetAlpha-1D adrenergic receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50: 560nMAssay Description:Inhibition of cloned adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50: 185nMAssay Description:Displacement of [3H]MK912 from human cloned adrenergic alpha-2a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50: 1.25E+3nMAssay Description:Displacement of [125I]-APT from histamine H2 receptor in brain of guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50: 2.35E+3nMAssay Description:Displacement of [3H]SMT from histamine H3 receptor in forebrain of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50: 2.35E+3nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]MK912 from human cloned adrenergic alpha-2a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataKi:  275nMAssay Description:Inhibition of cloned adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [125I]-APT from histamine H2 receptor in brain of guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]SMT from histamine H3 receptor in forebrain of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]SMT from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed