BDBM50252998 CHEMBL4105008

SMILES Clc1ccccc1-c1ccc(\C=N\NC(=O)CSc2nnc(Nc3ccccc3)s2)o1

InChI Key InChIKey=CAOQXDWNQZWERF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252998   

TargetCarbonic anhydrase 1(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252998(CHEMBL4105008)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of carbonic anhydrase-1 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252998(CHEMBL4105008)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252998(CHEMBL4105008)
Affinity DataKi:  0.640nMAssay Description:Competitive inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by Lineweave...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252998(CHEMBL4105008)
Affinity DataKi:  1.10nMAssay Description:Competitive inhibition of carbonic anhydrase-1 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by Lineweave...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed