BDBM50252886 (S)-1-(4-Methanesulfonamidophenoxy)-3-(4-chlorophenylethylamino)-2-propanol::CHEMBL492846

SMILES CS(=O)(=O)Nc1ccc(OC[C@@H](O)CNCCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=VMIBLDKZGHZFMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252886   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252886((S)-1-(4-Methanesulfonamidophenoxy)-3-(4-chlorophe...)
Affinity DataIC50: 101nMAssay Description:Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252886((S)-1-(4-Methanesulfonamidophenoxy)-3-(4-chlorophe...)
Affinity DataIC50: 1.39E+3nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed