BDBM50252521 CHEMBL492828::isoxanthohumol

SMILES [#6]-[#8]-c1cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-[#6](-[#6]-[#6](=O)-c12)-c1ccc(-[#8])cc1

InChI Key InChIKey=YBWLJTKGOURXMS-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50252521   

TargetBeta-secretase 1(Human)
Gyeongsang National University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252521(isoxanthohumol | CHEMBL492828)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50252521(isoxanthohumol | CHEMBL492828)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of human PKC alpha assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50252521(isoxanthohumol | CHEMBL492828)
Affinity DataIC50: 5.87E+4nMAssay Description:Inhibition of human PDK1 assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50252521(isoxanthohumol | CHEMBL492828)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human PKC theta assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Hallertauer Hopfenveredelung

Curated by ChEMBL
LigandPNGBDBM50252521(isoxanthohumol | CHEMBL492828)
Affinity DataEC50:  1.40E+3nMAssay Description:Estrogenic activity at estrogen receptor alpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-Nitrophenol pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed