BDBM50252338 CHEMBL4090364

SMILES CCN(CC)CCCC(C)Nc1nc(\C=C\c2c(Cl)cc(Cl)cc2Cl)nc2ccc(N)cc12

InChI Key InChIKey=SPVVMGWKAXMWAM-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50252338   

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BMX/ETK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MELK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MELK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of TIE2/TEK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetMegakaryocyte-associated tyrosine-protein kinase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of CTK/MATK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of LYN B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of CaMK2gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of CaMK2delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of ERBB4/HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50252338(CHEMBL4090364)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CaMK1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed