BDBM50251453 CHEMBL4079572

SMILES Nc1nccc(n1)-c1c[nH]c2cnccc12

InChI Key InChIKey=ULPADEPZZAIIOV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251453   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251453(CHEMBL4079572)
Affinity DataIC50: 1nMAssay Description:Inhibition of full-length recombinant human GST-tagged Dyrk1a expressed in baculovirus expression system using Alexa-Fluor tracer-236 incubated for 6...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251453(CHEMBL4079572)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of full-length recombinant human His-tagged GSK3B recombinant in baculovirus expression system using Alexa-Fluor tracer-236 incubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251453(CHEMBL4079572)
Affinity DataEC50:  4.80E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed