BDBM50251241 CHEMBL4098732

SMILES [#6]-[#8]-c1cc(ccc1-[#8])-c1cc(=O)c2c(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2o1

InChI Key InChIKey=XSGSJWYITJAKSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251241   

TargetProstaglandin E synthase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50251241(CHEMBL4098732)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cells microsomal membranes assessed as reduction in conversion of PGH2 to PGE2 pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50251241(CHEMBL4098732)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed