BDBM50251076 CHEMBL2397397

SMILES FC(F)(F)c1ccc(cc1)-c1nc2sc3CCCCCc3c2c(=O)[nH]1

InChI Key InChIKey=KIWJGGYJLIBLRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251076   

TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50251076(CHEMBL2397397)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50251076(CHEMBL2397397)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed