BDBM50250972 CHEMBL4080510

SMILES Cc1cc(cc(C)c1O)-c1nc2sc3CCCc3c2c(=O)[nH]1

InChI Key InChIKey=SJSIKYDYHSSABB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250972   

TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50250972(CHEMBL4080510)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50250972(CHEMBL4080510)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed