BDBM50250914 CHEMBL4091173

SMILES CC1(N)CCN(CC1)c1nc(cs1)-c1ccc2cc(Br)ccc2c1

InChI Key InChIKey=IJQCDAAODIMGGK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50250914   

TargetM-phase inducer phosphatase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of CDC25A (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMW-PTP (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed