BDBM50250184 4-(5-(4-Chlorophenyl)-3-(5-fluoro-2-methoxybenzoyl)-2-methyl-1H-pyrrol-1-yl)benzenesulfonamide::CHEMBL492176

SMILES COc1ccc(F)cc1C(=O)c1cc(-c2ccc(Cl)cc2)n(c1C)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=BVCWEXFYPSDGGF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50250184   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50250184(4-(5-(4-Chlorophenyl)-3-(5-fluoro-2-methoxybenzoyl...)
Affinity DataEC50:  1.05E+4nMAssay Description:Allosteric modulator activity at alpha7 nAChR in human IMR32 cells assessed as stimulation of agonist-induced intracellular calcium level by FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed