BDBM50250181 CHEMBL2338421::N''-(5-Benzofuroxanylmethylidene)Isoniazide

SMILES [O-][n+]1onc2ccc(\C=N\NC(=O)c3ccncc3)cc12

InChI Key InChIKey=VJMQKZDATXNVBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250181   

TargetCytochrome P450 2C8(Human)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50250181(N''-(5-Benzofuroxanylmethylidene)Isoniazide | CHEM...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50250181(N''-(5-Benzofuroxanylmethylidene)Isoniazide | CHEM...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50250181(N''-(5-Benzofuroxanylmethylidene)Isoniazide | CHEM...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50250181(N''-(5-Benzofuroxanylmethylidene)Isoniazide | CHEM...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed