BDBM50250173 CHEMBL4095780

SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(N)(=O)=O)c(=O)[nH]c2=O)ccc1F

InChI Key InChIKey=FTDANXPNKJENKV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250173   

TargetCollagenase 3(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250173(CHEMBL4095780)
Affinity DataIC50: 258nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250173(CHEMBL4095780)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250173(CHEMBL4095780)
Affinity DataIC50: 258nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250173(CHEMBL4095780)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed