BDBM50250172 CHEMBL4081325

SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)C(=O)N[C@@H](CO)C(O)=O)c(=O)[nH]c2=O)ccc1F

InChI Key InChIKey=QTTXNAZRANVJPE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250172   

TargetStromelysin-2(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250172(CHEMBL4081325)
Affinity DataIC50: 705nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250172(CHEMBL4081325)
Affinity DataIC50: 14nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250172(CHEMBL4081325)
Affinity DataIC50: 705nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Zhaw Zurich University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50250172(CHEMBL4081325)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed