BDBM50249953 CHEMBL491129::N-{4-[5-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)-pentyl]benzoyl}-L-glutamic Acid

SMILES Nc1nc2sc(CCCCCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=OBGKKSLNXVLXEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249953   

TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Wayne State University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50249953(N-{4-[5-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wayne State University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50249953(N-{4-[5-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of GARFTase in human KB cells assessed as inhibition of incorporation of [14C]glycine into [14C]formyl GAR after 30 mins in presence of az...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed