BDBM50249831 2-((4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl)isonicotinamide::CHEMBL489725

SMILES C[C@@H]1NC(=N[C@@]1(c1ccc(F)cc1)c1ccc(F)nc1)c1cc(ccn1)C(N)=O

InChI Key InChIKey=VMXBWFMRIFZHPT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249831   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249831(2-((4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]6-yl]methanesu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249831(2-((4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed