BDBM50249729 CHEMBL4060138

SMILES Cc1cc(CNc2nc(N)nc3ccn(Cc4cc(ccn4)C(F)(F)F)c23)no1

InChI Key InChIKey=BWOZJELILVACLA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249729   

TargetToll-like receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50249729(CHEMBL4060138)
Affinity DataEC50:  20nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IFNalpha-mediated inhibition of HCV genotype 1b RNA replication in human HuH luc/neo ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed