BDBM50249616 CHEMBL514966::{4-[(Benzylmethylamino)methyl]phenyl}-(4-methoxyphenyl)methanone

SMILES COc1ccc(cc1)C(=O)c1ccc(CN(C)Cc2ccccc2)cc1

InChI Key InChIKey=WQQMJTPJWKIZIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249616   

TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249616({4-[(Benzylmethylamino)methyl]phenyl}-(4-methoxyph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249616({4-[(Benzylmethylamino)methyl]phenyl}-(4-methoxyph...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249616({4-[(Benzylmethylamino)methyl]phenyl}-(4-methoxyph...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249616({4-[(Benzylmethylamino)methyl]phenyl}-(4-methoxyph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed