BDBM50249571 CHEMBL4101927::US10729695, Compound CB-6

SMILES COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1nccs1

InChI Key InChIKey=MBBUHPYZYTUFFC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249571   

TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249571(CHEMBL4101927 | US10729695, Compound CB-6)
Affinity DataKd:  0.300nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249571(CHEMBL4101927 | US10729695, Compound CB-6)
Affinity DataKd:  0.100nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In DepthDetails
US Patent