BDBM50249449 5-Amino-4-(1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-ylamino)-6-isobutylamino-pyrimidine-2-carbonitrile::CHEMBL474829

SMILES CC(C)CNc1nc(nc(NC2CCS(=O)(=O)C2)c1N)C#N

InChI Key InChIKey=BGDXMJHWJDPFBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249449   

TargetCathepsin K(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249449(5-Amino-4-(1,1-dioxo-tetrahydro-1lambda*6*-thiophe...)
Affinity DataIC50: 14nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed